Tissue
Cartilage
Cellular seed
Auricular-cartilage micrografts via Mytocel AMT
Soil
ChondroFiller
Signal
ArthroZheal PRF
Precision
A new environment at the joint surface
Professor Lee’s joint repair and regeneration hub
Protect the movementthat makes life yours.
Cartilage, tendon, meniscus and bone fail for different reasons. Professor Paul Lee’s NANO techniques share one fixed design principle—Seed · Soil · Signal—but change the biology, mechanics and delivery for the tissue being repaired.
Cartilage · NANO ACiTendon · NANO ATiMeniscus · NANO AMiBone · NANO AOi
The shared NANO logic
One organising method. Four different tissue problems.
Seed · Soil · Signal is the common grammar. The cell source, target anatomy, mechanics and recovery change with the tissue.
NANO ACi
Cartilage
Cartilage wear or damage
NANO ATi
Tendon
Disrupted collagen fibres
NANO AMi
Meniscus
Load-sharing tear
NANO AOi
Bone
Trabecular defect
- 01
Select target tissue
- 02
Harvest seed
- 03
Prepare soil
- 04
Add signal
- 05
Deliver precisely
- 06
Protect and measure recovery
Begin with the tissue—not the product
Four tissues. Four repair problems. Four distinct techniques.
“Regeneration” can sound like one category of injection. Professor Lee’s approach is more exact. Cartilage needs a new surface; tendon needs organised force transmission; the meniscus must distribute load; bone has to rebuild structure strong enough to carry weight.
The shared principle is a way of designing surgery: choose a tissue-relevant cellular seed, give it an environment, supply a biological signal and deliver it precisely. What changes from page to page is the part that matters most—the tissue itself.
Cartilage
NANO ACi
Rebuild the joint surface without taking the patient through a cartilage operation.
Tendon
NANO ATi
Bring a tissue-specific repair environment to a tendon that has stopped healing.
Meniscus
NANO AMi
Preserve the knee's load-sharing tissue and the movement that depends on it.
Bone
NANO AOi
Combine biological repair with the stability and load planning bone requires.
The shared design principle
Seed. Soil. Signal. Precision.
TissueCellular seedSoilSignalWhat precision means
Tissue
Tendon
Cellular seed
Tendon-focused autologous micrografts via Mytocel AMT
Soil
ChondroFiller
Signal
ArthroZheal PRF
Precision
The damaged tendon zone inside a loading plan
Tissue
Meniscus
Cellular seed
Meniscus-focused autologous micrografts via Mytocel AMT
Soil
ChondroFiller
Signal
ArthroZheal PRF
Precision
The tear, remaining tissue and whole-knee mechanics
Tissue
Bone
Cellular seed
Bone Marrow Aspirate Concentrate (BMAC)
Soil
ChondroFiller
Signal
ArthroZheal PRF
Precision
Stability, containment and controlled load
Dedicated pathway
Cartilage repair and regeneration
Cartilage has its own hub because patients may need established ACI, MACI, osteochondral grafting, ChondroFiller or Professor Lee’s NANO ACi technique. The hub separates each option and shows where it fits before replacement.
Explore the cartilage hubThe wider repertoire
Repair does not compete with replacement
Professor Lee remains a replacement and revision surgeon. Joint preservation is a question of timing: save viable tissue when that is realistic, and use replacement when it is the strongest answer—not because the treatment catalogue stops there.
See all clinical expertiseEvidence boundary
Each complete technique must earn its own authority
Mytocel AMT, ChondroFiller, ArthroZheal and BMAC each have their own evidence bases. Professor Lee’s NANO techniques are defined combinations with tissue-specific selection, preparation and delivery. Evidence for a component is useful context; it is not silently converted into proof of every combined protocol.
FAQ
Questions about joint repair and regeneration
The hub is designed to make the tissue differences clear before any individual procedure is considered.
Repair restores a damaged structure; regeneration aims to rebuild or improve the biological tissue itself. Professor Lee’s plans may use either or both, depending on what has failed and what the joint can still preserve.
No. They share Professor Lee’s fixed Seed · Soil · Signal design principle, but the target tissue, cellular source, mechanics, delivery and recovery plan change. Bone uses BMAC; cartilage, tendon and meniscus use tissue-specific autologous micrografts prepared through Mytocel AMT.
No. A torn structure may still need sutures, unstable bone may need fixation and an end-stage joint may need replacement. Professor Lee uses repair and regeneration inside a complete orthopaedic repertoire.
The decision starts with diagnosis, imaging, alignment, stability, tissue quality, loading and the patient’s goals. The newest option is not automatically the right option.
Start with what has failed—and what can still be saved
The right answer may preserve, repair, regenerate or replace
cartilagetendonmeniscusbonewhole-joint planning
Professor Lee’s role is to match the technique to the tissue, the mechanics and the person—not to force every joint into the same pathway.