Achilles tendon
The push-off that makes walking fast, running and climbing feel natural can become guarded or unreliable.
Tendon repair · World-first Professor Lee technique
A tendon should carry load.Not organise your life.
NANO ATi is Professor Paul Lee’s tissue-specific tendon repair technique. It builds Seed · Soil · Signal around the exact tendon problem—then delivers them as one precise procedure.
Tissue-specific autologous cellsMytocel AMT preparationChondroFiller soilArthroZheal signal
Clinical plate 01 · Tendon load path
Parallel fibres disrupted inside a loading system
Healthy tendon fibres organise force in one direction. Degeneration or a partial tear interrupts that pattern, but biology only helps when diagnosis and progressive loading are planned together.
Mechanical question
Define the tendon zone, tissue quality and load that repeatedly provokes it.
Regenerative opportunity
Support a tissue-specific repair environment, then teach the tendon to carry load again.
01Define the tissue before the technique
The NANO ATi pathway
Precision begins before anything is prepared
The process starts with the tendon diagnosis and its loading problem. Seed, soil and signal are supporting biological roles inside that larger plan—not substitutes for accurate targeting or progressive rehabilitation.
Stage 01
Select target tissue
Confirm the pain generator
Examination and imaging distinguish tendinopathy or a partial tear from referred pain, joint disease, nerve irritation or a rupture needing conventional repair.
Stage 02
Harvest seed
Autologous tissue source
Tendon-focused autologous micrografts prepared through Mytocel AMT provide the cellular starting material.
Stage 03
Prepare soil
Build the local environment
ChondroFiller collagen supplies the local soil intended to support and retain the biological preparation.
Stage 04
Add signal
Supply the biological instruction
ArthroZheal platelet-rich fibrin supplies the patient-derived biological signal.
Stage 05
Deliver precisely
Deliver, protect and progressively reload
The planned combination is delivered to the defined tendon zone under image guidance, followed by staged mechanical rehabilitation.
Stage 06
Protect and measure recovery
Let tendon biology meet the mechanical plan
The delivery is one stage of tendon repair. The staged return of load is how the treated tissue is asked to become useful again.
The biological integration
Seed · Soil · Signal
The organising logic stays constant. The clinical meaning changes with the source tissue, target anatomy and mechanics of repair.
Seed
Tendon-focused autologous micrografts prepared through Mytocel AMT provide the cellular starting material.
Soil
ChondroFiller collagen supplies the local soil intended to support and retain the biological preparation.
Signal
ArthroZheal platelet-rich fibrin supplies the patient-derived biological signal.
Same method · different target
The problem NANO ATi is designed around
Tendon pain is often a failed healing cycle
Tendons transmit force from muscle to bone. They are meant to tolerate thousands of repeated loads, but their blood supply is limited and their repair response can fall behind. The result is not simply inflammation: the collagen can become disorganised, the tendon thickens or tears, and ordinary load keeps restarting the same problem.
A pain-killing injection may quieten a symptom without changing that biology. A biological treatment may still fail if the wrong structure is targeted or loading is not corrected. Professor Lee designed NANO ATi to treat the tendon as both a living tissue and a mechanical cable.
Patellar tendon
Jumping, landing, stairs and rising from a chair repeatedly load the tendon at the front of the knee.
Rotator cuff
A tendon problem in the shoulder can take away sleep, strength and confident overhead movement.
Common extensor tendon
Tennis elbow can make ordinary gripping—lifting a kettle, opening a door, using tools—unexpectedly painful.
A useful way to picture it
A tendon is more like a rope than a cushion
01
Aligned fibres
Healthy collagen transfers force in an organised direction.
02
Repeated overload
Microdamage accumulates faster than the tissue can remodel.
03
Disorganised repair
The tendon may remain painful, weak or vulnerable to further tearing.
Professor Lee’s design response
Biology placed inside a loading plan
NANO ATi does not treat “tendon pain” as a generic destination for a needle. The structure is identified, the damaged zone is mapped, the biological roles are prepared, and delivery is integrated with the mechanical rehabilitation that follows.
Target
The exact tendon and pathological zone.
Seed
Autologous tissue micrografts prepared through Mytocel AMT.
Soil
ChondroFiller collagen provides the local environment and retention.
Signal
ArthroZheal platelet-rich fibrin prepared from the patient’s blood.
Function is the destination
A repaired tendon must tolerate useful load again
The goal is not simply to place biology into tissue. It is to restore a tendon’s capacity to transfer force through the movements that matter, using a rehabilitation plan that progressively tests and rebuilds that capacity.
Where it may fit
Persistent tendon damage that has not recovered through a well-run first-line pathway
NANO ATi may be discussed when the tendon diagnosis is clear, symptoms remain meaningful, rehabilitation has not restored function and the structure can realistically be approached through a biological, image-guided technique.
Discuss a tendon problemNot a shortcut
Some tendon problems need only time and intelligent loading. Others need surgical reattachment or reconstruction. A new technique is useful only when it is a better answer for the exact tissue problem—not simply because it is new.
Evidence boundary
The complete technique needs its own outcomes
Mytocel AMT, collagen scaffolds and platelet-rich fibrin each have relevant component evidence. NANO ATi is Professor Lee’s complete tendon-specific protocol. Evidence for one part is not presented as proof of the combined technique, and suitability remains an individual clinical decision.
FAQ
Questions about NANO ATi
Tendon repair depends on diagnosis, biology and load—so the answers are more useful than a treatment label alone.
NANO ATi is Professor Paul Lee’s tendon-specific repair and regeneration technique. It combines autologous tissue micrografts prepared through Mytocel AMT with ChondroFiller, ArthroZheal and image-guided delivery to a defined tendon target.
No. ArthroZheal platelet-rich fibrin provides the biological signal, but the complete technique also includes tissue-specific autologous micrografts as the seed, ChondroFiller collagen as the soil and Professor Lee’s planned delivery method.
Yes. Mytocel Autologous Micrografting Technology mechanically prepares the patient’s own selected tissue into the AMT micrograft solution used as the cellular seed within NANO ATi.
A complete rupture or a tendon that has pulled away from bone may require established surgical repair. NANO ATi is considered only after the tear pattern, tissue quality, mechanics and realistic alternatives have been assessed.
The biological procedure does not remove the need for progressive loading. Rehabilitation is planned around the tendon, chronicity and activity goal because repaired tissue must learn to tolerate load again.
Continue Reading
Continue through the repair family
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Understand how autologous tissue is mechanically prepared into the cellular micrograft solution.
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NANO AMi meniscus repair
See how the same biological design principle changes when the target is the knee’s load-sharing meniscus.
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Treat the tendon you have—not a generic pain label
Diagnosis and load planning come before biology
tear patterntissue qualityloadingprecisionrehabilitation
Professor Lee assesses whether NANO ATi, structured rehabilitation or established tendon surgery offers the strongest route back to function.