SHARE LOAD
Spread pressure across the joint
The meniscus enlarges the contact area between the femur and tibia so force is not concentrated on a small patch of cartilage.
Meniscus repair · Professor Lee technique
Keep the knee’snatural shock absorber.
NANO AMi is Professor Paul Lee’s meniscus-focused repair and regeneration technique. It is designed to preserve the tissue that shares load, guides movement and protects the cartilage—rather than treating the meniscus as expendable.
Meniscus preservationTissue-specific autologous cellsSeed · Soil · SignalWhole-knee planning
Clinical plate 01 · Meniscus load sharing
A crescent load distributor divided by a tear
The meniscus converts compressive load into circumferential tension. A radial or root tear can interrupt that hoop, increasing pressure on cartilage even when the damaged area looks small.
Mechanical question
Map tear stability, remaining tissue, alignment, ligaments and the adjacent cartilage surface.
Regenerative opportunity
Combine structural repair where required with biology adapted to viable meniscal tissue.
01Define the tissue before the technique
How NANO AMi is built
Biology adapted to meniscal tissue and knee mechanics
NANO AMi follows the fixed Seed · Soil · Signal principle, but the meniscus is not treated as cartilage with a new label. The tear pattern, remaining tissue and load-sharing mechanics determine whether biology is appropriate and whether structural repair is also required.
Stage 01
Select target tissue
Define the tear and whole-knee mechanics
Professor Lee maps the tear, remaining tissue, cartilage, alignment and stability before deciding whether a biological strategy belongs in the plan.
Stage 02
Harvest seed
Autologous tissue source
Meniscus-focused autologous micrografts prepared through Mytocel AMT provide the cellular starting material.
Stage 03
Prepare soil
Build the local environment
ChondroFiller collagen supplies the local soil intended to support and retain the biological preparation.
Stage 04
Add signal
Supply the biological instruction
ArthroZheal platelet-rich fibrin supplies the patient-derived biological signal.
Stage 05
Deliver precisely
Deliver precisely and protect load sharing
The planned combination is delivered to the defined target and followed by recovery that respects the repair and whole-knee mechanics.
Stage 06
Protect and measure recovery
Let meniscus biology meet the mechanical plan
The complete NANO AMi technique is the connection between diagnosis, structural repair where required, Seed · Soil · Signal, precise delivery and recovery.
The biological integration
Seed · Soil · Signal
The organising logic stays constant. The clinical meaning changes with the source tissue, target anatomy and mechanics of repair.
Seed
Meniscus-focused autologous micrografts prepared through Mytocel AMT provide the cellular starting material.
Soil
ChondroFiller collagen supplies the local soil intended to support and retain the biological preparation.
Signal
ArthroZheal platelet-rich fibrin supplies the patient-derived biological signal.
Same method · different target
What the meniscus actually does
A small structure with a very large job
Each knee has two crescent-shaped menisci between the thigh bone and shin bone. They spread force across the joint, improve congruence and contribute to stability. That is why a damaged meniscus can be felt during twisting, deep flexion, uneven ground and long periods on the feet—and why losing tissue can accelerate cartilage wear.
GUIDE MOVEMENT
Support rotation and deep bend
Its shape helps the knee remain congruent as the bones roll, glide and rotate through movement.
PROTECT CARTILAGE
Absorb shock over time
Preserving functional meniscal tissue is part of protecting the joint surface from avoidable overload.
The preservation decision
The treatment is chosen after four questions
A meniscus tear is not a complete diagnosis. The same line on an MRI can mean something very different in a stable, well-aligned knee than it does in a knee with ligament failure or established cartilage loss.
01
Is the tear mechanically unstable?
A displaced or locking tear may need structural repair before biology can help.
02
How much viable meniscus remains?
Tissue quality, location and blood supply influence whether preservation is realistic.
03
What is the knee doing to it?
Malalignment, ligament instability and repetitive overload can keep stressing the same area.
04
What has happened to the cartilage?
The meniscus and joint surface share load; neither can be planned in isolation from the other.
Movement worth protecting
The outcome is not an MRI. It is what the knee lets you do.
Meniscal preservation matters because real life is rarely a straight, level walk. Deep knee bend, rotation and changing ground all ask the meniscus to share load while the knee moves. That function—not simply the appearance of a tear—is what the plan seeks to protect.
Deep bendTurningUneven groundTime on your feet
The pathways are not interchangeable
Preserve first—but use the repair the knee actually needs
Pathway 01
Rehabilitation and load management
For stable symptoms without a repairable mechanical tear, strength, movement and progressive loading may be the most useful first treatment.
Pathway 02
Structural meniscus repair
Sutures, root repair or reconstruction may be required when the tissue has separated, displaced or lost its mechanical attachment.
Pathway 03
NANO AMi biological repair
A tissue-specific biological technique may be considered where the target, remaining tissue and whole-knee mechanics support that plan.
Evidence boundary
The tissue, the repair and the outcome must match
Evidence concerning autologous micrografts, collagen scaffolds or platelet-rich fibrin helps explain each biological role. NANO AMi is the complete meniscus-focused technique designed by Professor Lee. Claims for an individual component are not treated as proof of the full protocol, and a regenerative procedure cannot restore mechanical stability that has not been addressed.
FAQ
Questions about NANO AMi
Meniscus preservation starts with understanding what tissue remains and what the whole knee asks it to do.
NANO AMi is Professor Paul Lee’s tissue-specific meniscus repair and regeneration technique. It combines autologous micrografts prepared through Mytocel AMT with ChondroFiller, ArthroZheal and a planned delivery method.
The meniscus distributes load, absorbs shock and contributes to knee stability. Removing meniscal tissue can increase contact pressure on the cartilage, so Professor Lee preserves viable tissue whenever the pattern and biology make that realistic.
Not automatically. A mobile or repairable tear may need sutures to restore structure. NANO AMi is a biological technique considered within the wider preservation plan, which may include rehabilitation, surgical repair or another established approach.
Yes. Mytocel Autologous Micrografting Technology prepares the patient’s selected tissue into a point-of-care AMT micrograft solution used as the cellular seed within the wider technique.
That depends on how much tissue remains, its vascularity, the tear pattern, alignment, stability and the condition of the cartilage. Some knees need repair, meniscal replacement or an alignment procedure rather than a biological injection alone.
Continue Reading
Meniscus and cartilage belong to the same joint story
Cartilage repair and regeneration
See how cartilage preservation, repair and regeneration interact with meniscal function.
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Mytocel MSK
Understand the point-of-care micrograft preparation that supplies the cellular seed.
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NANO ATi tendon repair
Compare how Professor Lee adapts the same biological design principle to tendon tissue.
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Preserve the meniscus before the joint pays the price
The right plan may be rehabilitation, structural repair, biological repair—or a combination
load sharingtear patternalignmentstabilitycartilage
Professor Lee brings the tear pattern, alignment, stability, cartilage and patient goals into one decision.